Group picture, 2013
Welcome to Materials and Microfluidics Research Group!
Our mission is to develop new strategies/concepts for the synthesis and design of new nano- and micro-structured materials with advanced applications. We conduct fundamental and applied research at the intersection of science, engineering, biology, and medicine.
We aim at: (a) the synthesis, fabrication, and self-assembly of functional nanostructures for the development of renewable energy, for chemical sensing, and so on; (b) the study of biomineralization, and bioinspired/biomimetic nanocomposite materials with structural hierarchy; (c) the exploration of microfluidics and nanofluidics for chemical synthesis, biological study, and medical diagnostics.
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Three-dimensional reconstruction of nanoparticle vesicles composed of a single layer of highly ordered gold nanoparticles in the membrane using tomographic TEM (diameter of gold nanoparticles: 15 nm).
Near-infrared (NIR) light triggered burst release of encapsulated molecules from giant vesicles composed of a single layer of gold nanorods in the membrane (black: vesicles; white: NIR light spot; size of giant vesicles: ~2,000 nm).
P. Huang, J. Lin, W.W. Li, P.F. Rong, Z. Wang, S.J. Wang, X.P. Wang, X.L. Sun, M. Aronova, G. Niu, R.D. Leapman, Z.H. Nie*, X.Y. Chen*, Biodegradable Gold Nanovesicles with Ultra-strong Plasmonic Coupling Effect for Photoacoustic Imaging-Guided Photothermal Therap
y, Angew. Chem. Int. Ed. 2013
, 52, 13958–13964
J. Lin, S.J. Wang, P. Huang, Z. Wang, S.H. Chen, G. Niu, W.W. Li, J. He, D.X. Cui, G. M. Lu, X.Y. Chen*, Z.H. Nie*, Photosensitizer-loaded gold vesicles with strong plasmonic coupling effect for imaging-guided photothermal/photodynamic therapy
, ACS Nano
, 7, 5320–5329
J. He, X.L. Huang, Y.C. Li, Y.J. Liu, T. Babu, M.A. Aronova, S.J. Wang, Z.Y. Lu,* X.Y. Chen,* Z.H. Nie*, Self-assembly of amphiphilic plasmonic micelle-like nanoparticles in selective solvents
, J. Am. Chem. Soc., 2013
, 135, 7974–7984.
Z. L. Wu, M. Moshe, J. Greener, H. Therien-Aubin, Z.H. Nie*, E. Sharon*, E. Kumacheva*, Three-dimensional Shape Transformations of Hydrogel Sheets Induced by Small-Scale Modulation of Internal Stresses
, Nature Communications
, 4, 1586.
J. He, Z. J. Wei, L. Wang, Z. Tomova, T. Babu#, C. Y. Wang, X. J. Han, J.T. Fourkas, Z.H. Nie*, Hydrodynamically driven self-assembly of giant vesicles of metal nanoparticles for remotely triggered release
, Angew. Chem. Int. Ed
, 52, 2463-2468.
Z.J. Wei, J. He, T. Liang (high school student), H. Oh, J. Athas, Z. Tong, C.Y. Wang* and Z.H. Nie*, Autonomous self-healing of poly (acrylic acid) hydrogels induced by the migration of metal ions
, Polymer Chemistry
4601-4605. (Polymer Chemistry's Top 10 most-read rticles for Q3 2013).
J. He, B.Y. Yu, M. J. Hourwitz#, Y.J. Liu, M. T. Perez, J. Yang, Z.H. Nie*,Wet-chemical synthesis of amphiphilic rodlike silica particles and their molecular-mimetic assembly in selective solvents
, Angew. Chem. Int. Ed. 2012
, 51, 3628 –3633.
- Z.H. Nie, D. Fava, et al. Self-assembly of metal-polymer analogues of amphiphilic triblock copolymers, Nat. Mater. 2007, 6, 609-614.