Group picture, 2013
Welcome to Materials and Microfluidics Research Group!
Our mission is to develop new strategies/concepts for the synthesis and design of new nano- and micro-structured materials with advanced applications. We conduct fundamental and applied research at the intersection of science, engineering, biology, and medicine.
We aim at: (a) the synthesis, fabrication, and self-assembly of functional nanostructures for the development of renewable energy, for chemical sensing, and so on; (b) the study of biomineralization, and bioinspired/biomimetic nanocomposite materials with structural hierarchy; (c) the exploration of microfluidics and nanofluidics for chemical synthesis, biological study, and medical diagnostics.
Please enter to see more details >>
Click to play
Three-dimensional reconstruction of nanoparticle vesicles composed of a single layer of highly ordered gold nanoparticles in the membrane using tomographic TEM (diameter of gold nanoparticles: 15 nm).
DPD simulation of the time-dependent self-assembly of nanoparticles grafted with amphiphilic block copolymers into hollow plasmonic vesicles.
The use of assembled plasmonic vesicles for photoacoustic imaging of tumors in mice.
Near-infrared (NIR) light triggered burst release of encapsulated molecules from giant vesicles composed of a single layer of gold nanorods in the membrane (black: vesicles; white: NIR light spot; size of giant vesicles: ~2,000 nm).
Reversible shape transformation of 2D hydrogel sheets into 3D helical structure.
P. Huang, J. Lin, W.W. Li, P.F. Rong, Z. Wang, S.J. Wang, X.P. Wang, X.L. Sun, M. Aronova, G. Niu, R.D. Leapman, Z.H. Nie*, X.Y. Chen*, Biodegradable Gold Nanovesicles with Ultra-strong Plasmonic Coupling Effect for Photoacoustic Imaging-Guided Photothermal Therap
y, Angew. Chem. Int. Ed. 2013
, 52, 13958–13964
J. Lin, S.J. Wang, P. Huang, Z. Wang, S.H. Chen, G. Niu, W.W. Li, J. He, D.X. Cui, G. M. Lu, X.Y. Chen*, Z.H. Nie*, Photosensitizer-loaded gold vesicles with strong plasmonic coupling effect for imaging-guided photothermal/photodynamic therapy
, ACS Nano
, 7, 5320–5329
J. He, X.L. Huang, Y.C. Li, Y.J. Liu, T. Babu, M.A. Aronova, S.J. Wang, Z.Y. Lu,* X.Y. Chen,* Z.H. Nie*, Self-assembly of amphiphilic plasmonic micelle-like nanoparticles in selective solvents
, J. Am. Chem. Soc., 2013
, 135, 7974–7984.
Z. L. Wu, M. Moshe, J. Greener, H. Therien-Aubin, Z.H. Nie*, E. Sharon*, E. Kumacheva*, Three-dimensional Shape Transformations of Hydrogel Sheets Induced by Small-Scale Modulation of Internal Stresses
, Nature Communications
, 4, 1586.
J. He, Z. J. Wei, L. Wang, Z. Tomova, T. Babu#, C. Y. Wang, X. J. Han, J.T. Fourkas, Z.H. Nie*, Hydrodynamically driven self-assembly of giant vesicles of metal nanoparticles for remotely triggered release
, Angew. Chem. Int. Ed
, 52, 2463-2468.
Z.J. Wei, J. He, T. Liang (high school student), H. Oh, J. Athas, Z. Tong, C.Y. Wang* and Z.H. Nie*, Autonomous self-healing of poly (acrylic acid) hydrogels induced by the migration of metal ions
, Polymer Chemistry
4601-4605. (Polymer Chemistry's Top 10 most-read rticles for Q3 2013).
J. He, B.Y. Yu, M. J. Hourwitz#, Y.J. Liu, M. T. Perez, J. Yang, Z.H. Nie*,Wet-chemical synthesis of amphiphilic rodlike silica particles and their molecular-mimetic assembly in selective solvents
, Angew. Chem. Int. Ed. 2012
, 51, 3628 –3633.
- Z.H. Nie, D. Fava, et al. Self-assembly of metal-polymer analogues of amphiphilic triblock copolymers, Nat. Mater. 2007, 6, 609-614.